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FUNCTIONAL TESTING

What you don't know may be harming you.

Test Tubes

Let's dive deeper into understanding what could be at the root cause of your frustrating symptoms and condition. The testing options are done through Great Plains Laboratories, SpectraCell and Meridian Valley, Gx Sciences and Nutrition Genome. Some of the test can be done at home, do not require a doctor or physician to request or read the results.

Functional Testing: About

IgG Food Sensitivities Test

$250

The IgG Food MAP With XMAP® Technology is a delayed IgG Food Sensitivity Panel provided

through Great Plains Laboratory, testing a full range of 190 food items common in the Western, Asian, and Mediterranean diets, even Hemp plus Candida and Yeast infections. Learn more: https://www.greatplainslaboratory.com/food-map-igg-sensitivity-profile

At home Blood Spot Test Kit or Serum Blood Draw Test Kit can be sent to your home. Blood Serum require a laboratory at a local hospital, children's hospital, Urgent Care, Local Medical School or contact your insurance to find a laboratory in your area.


*Test kits take 3-5 days to reach your address and processed in 8-10 days with test results through email to me. I provide Test Results Review Consultations with recommendations. See the Consultations Page here to book the appointment about 3 weeks out to go over the results and devise a plan with the information.

To place the order, the following is needed: Name of person being tested, DOB, weight, address, email address, phone number. 


Make the payment to PayPal at: paypal.me/nourishrevivethrive

(NOTE: If using a Credit Card please add 3% to cover the processing fees.)


These tests are not usually covered by insurance and seen as preventative testing deemed not necessary. Blue Cross Blue Shield, Tricare, Medicare may offer partial to full coverage for some tests. You will have to contact your own insurance provider to find out their coverage.

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Hair Heavy Metals Test

$225

Hair Elements analysis provides information regarding recent and ongoing exposure to potentially toxic and neurotoxic metals such as methylmercury, arsenic, aluminum, tin, cadmium, lead, antimony and mercury and time-averaged status of specific nutrient elements (minerals) which plays a key role in essential mineral balances/deficiencies or toxic abnormalities.


The CDC acknowledges the value of hair mercury levels as a maternal and infant marker for exposure to neurotoxic methylmercury from particular large fish.


This noninvasive screening test requires only .25 grams of hair. Toxic elements may be 200 to 300 times more highly concentrated in hair than in blood or urine. Therefore, hair is the tissue of choice for detection of recent exposure to toxic elements.


You will receive a kit from Great Plains Laboratory within 3-5 business days after payment is made. Make the payment to PayPal at: paypal.me/nourishrevivethrive

(NOTE: If using a Credit Card please add 3% to cover the processing fees.)

It takes 10-12 days for the test results to be posted via email. This test can be done at home with hair samples. Please allow one inch of hair to grow out or use pubic hairs. Follow instructions on kit once received.


To request kit provide pertinent client information via email by clicking request test: Name, DOB, Weight, Address, Email and Phone Number.

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Organic Acids Test

$350

The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient’s overall health with 76 markers. It provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids in their urine. The cause of these high levels could include oral antibiotic use, high sugar diets, immune deficiencies, acquired infections, as well as genetic factors.

The Organic Acids Test also includes markers for vitamin and mineral levels, oxidative stress, neurotransmitter levels, and is the only OAT to include markers for oxalates, which are highly correlated with many chronic illnesses.

If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test.

To order the test click request test and provide the pertinent information: name, DOB, address, email address, phone number. Make the payment to PayPal at: paypal.me/nourishrevivethrive

(NOTE: If using a Credit Card please add 3% to cover the processing fees.)


Shipping takes 3-5 days for the test kit to arrive, 12 days to receive results by email.



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Functional Testing: Projects
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ADDITIONAL TESTING

FUNCTIONAL TESTING

IgG Food Sensitivity, Heavy Metals, Organic Acids, Environmental Toxins, Comprehensive Stool Analysis Gut/Microbiome, MTHFR Genotyping, Genetic Testing

Meridian Valley: The Combined Health Screen (CHS) $275

The Combined Health Screen panel  combines several commonly-ordered screening panels and markers into a single, easy-to-order and cost-effective panel. This panel includes:

  1. Comprehensive Metabolic Panel (CMP),

  2. Lipid Panel,

  3. Complete Blood Count (CBC) with differential and platelets 

  4. Analytes 


An extended panel is also available, as well as panels with additional special focus analytes. (See below.) 


Extended Combined Health Screen 


Combined Health Screen with Homocysteine 


Combined Health Screen with Ferritin 


Combined Health Screen with Mini-Thyroid (Includes TSH, Free T4, Free T3)

Indications:

  • General screening for a broad range of health, cardiovascular, and nutritional concerns.

  • Suspected methylation disorder or cardiovascular disease (CHS-H) · Suspected low or high iron status (CHS-F) ·

  • Suspected thyroid dysfunction (CHS-T).   


Great Plains Laboratory Mold IgE Allergy Test – Serum $200

Can be included with MycoTox $450

The Mold IgE Allergy panel includes 13 mold allergens, with markers known to be involved in mold-related illnesses.

Mold allergy is an abnormal immune reaction to mold spores or mold cell components. People can be exposed to mold spores or byproducts at work, home or outdoors.

The Great Plains Laboratory offers an IgE blood test that measures patient antibodies to most common molds. The IgE antibodies are detected in blood serum using an FDA-approved enzyme-linked immunosorbent assay (ELISA).

The most common molds known to cause allergic conditions include Alternaria, Aspergillus, Cladosporium and Penicillium. Use of both tests allow a wider array of molds to be detected.


Advantages of IgE Mold Allergy Testing:

  • IgE Mast Cell Inflammatory Mediators

  • Identify IgE reactivity level to specific mold species.

  • Connect immune responses to specific molds.

  • Suggest history of mold exposure.

  • Current higher reactivity or potential past lower reactivity.

  • Helpful for individuals with allergies, asthma and other respiratory conditions that may be due to histamine release and other inflammatory mediators resulting from IgE reactivity or other immune reactions.

  • Link IgE results with mold allergy symptoms, which include cough and postnasal drip, watery eyes, itchy eyes, nose, throat, runny or stuffy nose, or dry, scaly skin. In addition, possibly assist in identifying abnormal reactions to mold, including mold-induced asthma, allergic bronchopulmonary aspergillosis, allergic fungal sinusitis, hypersensitivity pneumonitis, and dampness and mold hypersensitivity syndrome (DMHS).

  • Certain occupations have potential for high mold exposure: crop and dairy farming, greenhouse plant husbandry, logging, carpentry, millwork, furniture repair and commercial baking.

  • A high exposure in the home can occur in damp areas such as bathrooms, kitchens and basements.

  • In general, working or living in damp buildings with moisture higher than 50% humidity, increases the possibility of mold exposure.

  • Immune reactions to mold can be identified by the level of immunoglobulin E (IgE) antibodies to specific mold species.




MycoTOX Profile (Mold Exposure) $300


Mycotoxins (toxins from mold) are some of the most prevalent toxins in the environment. Mycotoxins are metabolites produced by fungi like mold, which can infest buildings, vehicles, and foodstuffs. Most mycotoxin exposures in North America, Europe, and Australia are through airborne exposure. Food may be a major source of mycotoxins in third-world nations that lack government inspection of foods, especially the grains such as rice, corn, wheat, rye, and barley. Many grains that are harvested have been found to be contaminated with mycotoxins but little of such harvests are discarded and are frequently sold for animal feeds such as dog food or feed for cows, pigs, chickens, turkeys, and horses.


Fungi can grow on almost any surface, especially if the environment is warm and wet. Inner wall materials of buildings, wallpaper, fiber glass insulation, ceiling tiles, and gypsum support are all good surfaces for fungi to colonize. These fungi then release mycotoxins into the environment causing symptoms of many different chronic diseases. Diseases and symptoms linked to mycotoxin exposure include fever, pneumonia-like symptoms, heart disease, rheumatic disease, asthma, sinusitis, cancer, memory loss, vision loss, chronic fatigue, skin rashes, depression, ADHD, anxiety, and liver damage. With the MycoTOX Profile we can identify mycotoxin exposures and make recommendations for detoxification treatments that have been effective. 


MycoTOX screens for eleven different mycotoxins, from 40 species of mold, in one urine sample.


GPL currently measures 11 different mycotoxins in our test from a wide variety of 13 mold types (genera) including Aspergillus, Penicillium, Fusarium, Myrothecium, Stachybotrys, Bipolaris, Gibberella, Chaetomium, Trichoderma, Trichothecium, Cephalosporium, Verticimonosporium, and Monascus. Since each of these genera contain multiple species, the MycoTOX Profile is likely to detect hundreds of mold species. In addition, poisonous mushrooms also produce some of the same mycotoxins as the molds. This makes the MycoTOX Profile the most comprehensive test on the market and it is the most cost-effective.  https://www.greatplainslaboratory.com/gplmycotox


GPL-TOX (173 Toxic Non-Metal Chemicals) $220


Every day, we are exposed to hundreds of toxic chemicals through products like pharmaceuticals, pesticides, packaged foods, household products, and environmental pollution. As we have become more exposed to chemical-laden products and to toxic chemicals in food, air, and water, we have been confronted with an accelerating rate of chronic illnesses like cancer, heart disease, chronic fatigue syndrome, chemical sensitivity, autism spectrum disorders, ADD/AD(H)D, autoimmune disorders, Parkinson’s disease, and Alzheimer’s disease. 


Because exposure to environmental pollutants has been linked to many chronic diseases, The Great Plains Laboratory has created GPL-TOX, a toxic non-metal chemical profile that screens for the presence of 173 different toxic chemicals including organophosphate pesticides, phthalates, benzene, xylene, vinyl chloride, pyrethroid insecticides, acrylamide, perchlorate, diphenyl phosphate, ethylene oxide, acrylonitrile, and more. This profile also includes Tiglylglycine (TG), a marker for mitochondrial disorders resulting from mutations of mitochondrial DNA. These mutations can be caused by exposure to toxic chemicals, infections, inflammation, and nutritional deficiencies.

  • GPL-TOX uses the power of advanced mass spectrometry (MS/MS), which is necessary to detect lower levels of certain genetic, mitochondrial, and toxic chemical markers that conventional mass spectrometry often misses.

  • GPL-TOX also includes Tiglylglycine, a marker for mitochondrial damage, which is often seen in chronic toxic chemical exposure.


https://www.greatplainslaboratory.com/tox-download

ENVIROtox Panel $580


Includes OAT (Organic Acids Test), GPL-TOX (Toxic Environmental Chemicals), Glyphosate Test (Insecticide)

ENVIROtox Complete Panel $840


Includes: Organic Acids Test, GPL-TOX: (Toxic Environmental Chemicals), Glyphosate Test, MycoTOX. (Mycotoxins, toxic metabolites from mold). https:// GPL_Test_EnviroTOX-TOXcomplete.pdf

Comprehensive GI/Stool Analysis with Parasitology $450


Through Great Plains Laboratory


The Comprehensive Stool Analysis detects the presence of pathogenic microorganisms such as yeast, parasites, and bacteria that contribute to chronic illness and neurological dysfunction — now with 14 new pathogen markers! It provides helpful information about prescription and natural products effective against specific strains detected in the sample. The test also evaluates beneficial bacteria levels, intestinal immune function, overall intestinal health, and inflammation markers.


Many chronic disorders come from digestive problems and inadequate nutrient absorption. Proper gastrointestinal function is needed to eliminate toxic substances, pathogenic microbes, and undigested food particles from the body to prevent health problems. Nutrients require a specific internal environment to be properly digested and transported throughout the body.


Abnormal intestinal microorganisms in the GI tract are widely known to cause disease. Research shows a relationship between the GI tract and the neurological, hepatic, and immune systems. For example, excessive yeast produces toxic substances that can pass through the blood-brain barrier and alter neurological functioning causing “brain fog,” behavior problems, and learning difficulties.


THE COMPREHENSIVE STOOL ANALYSIS INCLUDES:


  • Parameters for digestion & absorption

  • Cultures for bacteria and yeast

  • Parasite testing

  • Sensitivity panels

  • Inflammatory markers

  • Stool metabolic markers

  • Infectious pathogens


THE BENEFITS OF COMPREHENSIVE STOOL ANALYSIS:


  • The amount of beneficial bacteria in the GI tract is determined

  • The digestive parameters aid in the diagnosis of intestinal dysfunction without invasive procedures

  • Inflammation and immune markers will aid in appropriate treatments

  • Many different pathogens have the potential to be isolated and identified


SPECIMEN REQUIREMENTS:


Stool: Sample must be collected on two separate days (at least 12 hours apart). The specimen must be received within 7 days of the first collection. The patient must discontinue digestive enzymes, antacids, iron supplements, vitamin C over 250 mg, aspirin, anti-inflammatories, and large amounts of meat 48 hours prior to the collection of the specimen.


https://www.greatplainslaboratory.com/comprehensive-stool-analysis https://static1.squarespace.com/ComprehensiveStoolAnalysisSampleReport.pdf

For a complete listing off all testing options through GPL: https://www.greatplainslaboratory.com/select

Micronutrient Test through Spectacell Labs $450


This test measures 31 vitamins, minerals, amino/fatty acids, antioxidants, and metabolites – and how they affect cellular function in a person. Correlating micronutrient deficiencies not only slows aging and degenerative disease progression, it can also prevent as well as repair cellular dysfunction, and by extension, disease. https://www.spectracell.com/micronutrient-test-panel

DNA Methylation Pathway Profile- Great Plains Laboratory (Saliva) $455

The identification of SNPs and their impact on health and physiology is an ongoing area of research – the hope is that finding and studying these small variations in DNA will lead to better and more individualized medical interventions.  In many cases the environment – diet, nutrition, toxicant exposures, stress - may further modify the expression of genes and SNPs. The SNPs affecting detoxification and methylation become even more important if a patient has been exposed to the toxicants such as mercury, lead or bisphenol A (BPA).  Lead and BPA inhibit the function of methyltransferases, and mercury inhibits methionine synthase, an important enzyme in the re-methylation of homocysteine.  Methylation is an essential step in the detoxification and elimination of arsenic and other xenobiotics.  Normal methionine metabolism is a critical component of Phase II detoxification processes; the B-12 and folate-dependent transmethylation and B-6 dependent transsulfuration pathways convert homocysteine to cysteine.  Cysteine is an important precursor in glutathione biosynthesis.The greatest difficulty in interpreting SNP results is determining the extent to which a DNA genotype is phenotypically expressed.  Other metabolic tests, such as our Organic Acids Test (OAT), combined with evaluation of the patient’s symptoms and responses to intervention, are necessary to assess the influence of known SNPs on the phenotype.  Identifying SNPs that influence health and disease risk allows clinicians to support their patients with appropriate lifestyle changes and nutrition to maximize health and wellness.


VDR: (the vitamin D receptor) is a nuclear receptor protein that binds 1,25-dihydroxy vitamin D to activate a signaling molecule that is believed to have important roles in a 3rd of the human genome. Some functions that are known are xenobiotic detoxification.


BHMT: (betaine-homocysteine methylatransferase) is a transferase enzyme that catalyzes the transfer of a methyl group from betaine to homocysteine, which produces methionine. Other enzymatic roles for BHMT is the choline oxidation processes. This enzyme is found in the liver and kidney.


COMT: (catechol-O-methyltransferase) functions in the nerve cells, liver, kidneys, and red blood cells. Its role is to help inactivate 2- and 4-hydroxyestradiols, and catecholamine hormones prior to excretion of bile. COMT is also found in the CNS where its role is the degradation of catecholamine neurotransmitters.


MAO A: (monoamine oxidase type A) its main role is to detoxify biological and xenobiotic amines. This enzyme also degrades neurotransmitters in both the central and peripheral nervous system.

AHCY: (adenosylhomocysteinase) an enzyme that breaks down methionine by converting S-adenosylhomocysteinase into homocysteine. This reaction regulates the methylation of other compounds.



CBS: (cystathionine beta-synthase) this enzyme is responsible for using vitamin B6 to convert serine and homocysteine into cystothionine which will be later converted into cysteine.


MTHFR: (methylenetetrahydrofolate reductase) enzyme responsible for the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This reaction allows for the conversion of homocysteine to methionine.


MTR: (methionine synthase) enzyme that catalyzes the re-methylation of homocysteine to methionine using the methyl-B-12 as a cofactor.


MTRR: (methionine synthase reductase) responsible for the regeneration of methyl-B-12.


SHMT: (serine hydroxymethyltransferase) responsible for catalyzing the interconversion of glycine to serine.


SUOX: (sulfite oxidase) mitochondrial enzyme responsible for oxidizing sulfites to sulfates. Sulfites are produced by the transsulfuration cycle or from diet.


MTHFR Gene Testing through Spectracell Labs $125


MTHFR is an enzyme responsible for converting 5, 10-methylenetetrahydrofolate to the product 5-methyltetrahydrofolate - it is involved in the metabolism of folate and homocysteine. The product of the reaction catalyzed by MTHFR converts homocysteine (a potentially toxic amino acid) to methionine (a useful and necessary amino acid). People with high homocysteine levels and those who have a familial history of cardiovascular disease, stroke or thrombosis should consider being tested. Methylation refers to the biochemical pathway in which methyl groups (one carbon and three hydrogen atoms) are added to molecules. Because it is involved in nearly all of the body’s functions, it contributes to countless biological processes including:


  •  Detoxification

  •  Energy production

  •  Genetic expression/DNA repair

  •  Inflammatory, immune, and stress response

  •  Neurotransmitter balance

  •  Production and recycling of glutathione

An inability to methylate properly can disrupt any of these processes, ultimately compromising one’s health as the body is not able to effectively respond due to the shortage of methyl groups. Impaired detoxification, cardiovascular disease, neurological problems, and weakened immune functioning in general, are some conditions linked to undermethylation.


This is a blood serum test with a 11-13 days turn-around time.


https://www.spectracell.com/mthfr-genotyping


https://assets.speakcdn.com/assets/2606/mthfr-genotyping-educational-sheet.pdf


https://www.youtube.com/watch?v=BhNtNBX8erk




GX Sciences Methylation Pathways Foundation/Methylation/Wellness Nutrigenomic Panel $350


21 genes have been chosen by our experts to be analyzed for SNPs (single nucleotide polymorphisms). There are as many as 50+ variants of the MTHFR gene. However, only two are considered ‘common’ defects that today’s MTHFR Blood Test checks for and are the: 677 and 1298 used in over 250 biochemical processes in the body.

https://gxsciences.com/nutrigenomics/foundation-methylation-wellness-panel/

DNA Test Kit + Whole Body Health Report through Nutrition Genome $305


  • Report updates for life

  • Personalized grocery list

  • Recommended blood work

  • Toxins / foods to avoid

  • Genetic strengths & weaknesses recap

  • 100 clinically relevant genes (151 SNPs) for a whole-body approach to wellness

  • 8 targeted reports profiling Digestion, Energy, Hormones, Stress & Cognitive Performance, Inflammation & Longevity, DNA Repair, Detoxification, and Athletic Performance


https://nutritiongenome.com/shop-nutrition-genome/


*Most Insurance Companies will not process these functions tests.

Functional Testing: Welcome
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